在针对性药物问世前，治疗手段十分有限且充满挑战。外科肢体延长术创伤性强、风险高，且行业内尚未形成统一诊疗共识；重组人生长激素（rhGH）虽能在一定程度上改善生长状况，但疗效有限，治疗2年后骨骼生长的有益作用便会减弱，还存在显著的长期副作用。
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But how much do you remember about Manchester's biggest Brits moments?
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It isn’t just celebrities like George Clooney packing up for France. Places like Portugal, Spain, and the Netherlands have seen American expat populations double lately, and Germany and Ireland both received more American arrivals last year than the other way around.